Understanding how certain proteins influence brain tumor development
Defining transcriptional networks and chromatin conformations regulating glioma tumorigenesis
This study is looking into how certain proteins and cell structures help brain tumors called gliomas grow, with the goal of finding better treatments for people affected by these tumors.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11049198 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind malignant gliomas, the most common and deadly type of brain tumor. It focuses on how specific transcription factors and chromatin structures contribute to tumor formation by regulating the fate of glial cells. By studying these processes, the research aims to uncover new insights that could lead to improved treatment strategies for glioma patients. The approach includes using advanced techniques to analyze gene regulatory programs involved in glioma development.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with malignant gliomas or those at risk due to genetic factors.
Not a fit: Patients with non-malignant brain tumors or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that improve survival rates for glioma patients.
How similar studies have performed: Previous research has shown promise in understanding glioma biology through similar approaches, indicating potential for impactful findings.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Glasgow, Stacey Marie — University of California, San Diego
- Study coordinator: Glasgow, Stacey Marie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.