Understanding how certain proteins influence appetite through endocannabinoid signaling
Molecular Drivers of FABP-mediated Endocannabinoid Signaling for Appetite Regulation
This study is looking at how certain proteins in our body help control our appetite by working with natural chemicals called cannabinoids, which could help us understand why some people gain weight while others stay lean, and it’s a great opportunity for trainees from different backgrounds to learn together.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | City College of New York NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11170259 on NIH RePORTER |
What this research studies
This research investigates the role of fatty acid-binding proteins (FABPs) in regulating appetite through the signaling of endogenous cannabinoids (ECs). By examining how these proteins interact with ECs and their effects on metabolic processes, the study aims to uncover mechanisms that could lead to obesity or lean outcomes. The research will involve laboratory experiments to analyze the binding and transport of ECs at physiological levels, providing insights into how these interactions affect appetite regulation. Trainees from diverse backgrounds will participate in this research, contributing to a collaborative learning environment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity or metabolic disorders related to appetite regulation.
Not a fit: Patients who do not have issues with appetite regulation or obesity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing appetite and obesity, potentially improving weight management and metabolic health for patients.
How similar studies have performed: While the specific interactions being studied are novel, previous research has shown that understanding metabolic signaling can lead to significant advancements in obesity treatment.
Where this research is happening
New York, United States
- City College of New York — New York, United States (Active)
Researchers
- Principal investigator: Stark, Ruth E. — City College of New York
- Study coordinator: Stark, Ruth E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.