Understanding how certain proteins influence appetite through endocannabinoid signaling
Molecular Drivers of FABP-mediated Endocannabinoid Signaling for Appetite Regulation
This study is looking at how certain proteins in our body might help control our appetite by working with natural chemicals called endocannabinoids, which could help us understand why some people gain weight while others stay lean, and it's also a great opportunity for trainees from different backgrounds to get involved in science.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | City College of New York NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11159310 on NIH RePORTER |
What this research studies
This research investigates the role of fatty acid-binding proteins (FABPs) in regulating appetite by interacting with endocannabinoids (ECs). By studying how these proteins transport or sequester ECs, the research aims to uncover mechanisms that could lead to obesity or lean outcomes. The approach involves in vitro experiments to analyze the binding and metabolic processes of these proteins and their complexes. The study also emphasizes the involvement of trainees from diverse backgrounds, promoting inclusivity in scientific research.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity or metabolic disorders related to appetite regulation.
Not a fit: Patients who do not have issues related to appetite regulation or obesity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for appetite regulation and obesity management.
How similar studies have performed: Previous research has shown promising results in understanding the role of endocannabinoids in appetite regulation, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- City College of New York — New York, United States (Active)
Researchers
- Principal investigator: Stark, Ruth E. — City College of New York
- Study coordinator: Stark, Ruth E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.