Understanding how certain proteins help cells communicate and adapt during development and stress.
Proteolytic Mechanisms Mediating Cell State Transitions in Development and Stress Responses
['FUNDING_OTHER'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-11011408
This study is looking at how certain proteins called caspases help cells communicate, move, and respond to stress, which could lead to new treatments for patients by understanding how these proteins work in our bodies.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-11011408 on ClinicalTrials.gov |
What this research studies
This research investigates the roles of caspases, a type of protein, in various cellular processes such as communication, migration, and stress responses. By examining how these proteins interact with other cellular components, the study aims to uncover their non-lethal functions during development. The approach includes advanced techniques like genetic screens and biochemical analyses to explore how caspases influence cell behavior and fate. Patients may benefit from insights gained about cellular mechanisms that could lead to new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions related to cellular communication and stress responses.
Not a fit: Patients with conditions unrelated to cellular signaling or development may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance cellular resilience and communication, potentially improving outcomes for various diseases.
How similar studies have performed: Other research has shown promising results in understanding the roles of caspases in cellular functions, indicating that this approach has potential for significant discoveries.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WEAVER, BENJAMIN P. — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: WEAVER, BENJAMIN P.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.