Understanding how certain proteins affect fat cell development and function
Elucidating ACLP-dependent signaling pathways in the adipose tissue stromal-vascular niche
['FUNDING_R01'] · BOSTON UNIVERSITY MEDICAL CAMPUS · NIH-11064872
This study is looking at a protein called ACLP to see how it affects fat cells and their role in storing fat or causing inflammation, which could help find new treatments for obesity and related health problems.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON UNIVERSITY MEDICAL CAMPUS (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11064872 on ClinicalTrials.gov |
What this research studies
This research investigates the role of a protein called ACLP in the signaling pathways within the fat tissue environment. It aims to understand how ACLP influences the development of fat cells and their ability to either store fat or contribute to inflammation and metabolic diseases. By focusing on the interactions in the adipose tissue stromal-vascular niche, the study seeks to identify potential therapeutic targets for obesity-related complications. Patients may benefit from insights that could lead to new treatments for obesity and its associated health issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity or related metabolic conditions such as diabetes.
Not a fit: Patients who are not affected by obesity or metabolic disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating obesity and its related metabolic disorders.
How similar studies have performed: Previous research has shown promising results in targeting signaling pathways in fat tissue for obesity treatment, indicating that this approach may be viable.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON UNIVERSITY MEDICAL CAMPUS — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LAYNE, MATTHEW D — BOSTON UNIVERSITY MEDICAL CAMPUS
- Study coordinator: LAYNE, MATTHEW D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.