Understanding how certain proteins affect facial development and related disorders
Official title: Investigating the Role of Heterotrimeric G Proteins in Craniofacial Development and Auriculocondylar Syndrome
Funded at University of Colorado Denver · NIH-10843241 · Data updated 2026-11-12
This study is looking into how our genes help shape our faces and how problems in this process can lead to conditions like Auriculocondylar Syndrome, with the hope that what we learn can lead to better treatments for people affected by these issues.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | August 1, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $133,134 |
| NIH project number | 5K99DE032428-02 |
| Project ID | NIH-10843241 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with craniofacial disorders or those interested in genetic factors affecting facial development.
✕Less likely to help
Patients without craniofacial disorders or those not affected by genetic factors related to facial development may not receive benefit from this research.
What this research studies
This research investigates the genetic and molecular mechanisms involved in craniofacial development, particularly focusing on the role of heterotrimeric G proteins. By utilizing advanced techniques such as genome-wide sequencing and genetic models like zebrafish, the research aims to uncover the underlying causes of craniofacial disorders, including Auriculocondylar Syndrome. Patients may benefit from insights gained that could lead to new therapeutic strategies for these conditions. The research is supported by a team of experienced mentors and is conducted in a collaborative environment.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for craniofacial disorders.
How similar studies have gone: Previous research has shown promise in understanding craniofacial development through genetic and molecular approaches, indicating potential for success in this area.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Kanai, Stanley Michinobu — University of Colorado Denver
- Study coordinator: Kanai, Stanley Michinobu
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.