Understanding how certain proteins affect facial development and function.
Official title: Investigating craniofacial phenotypes, cellular function, and membrane biochemistry of ciliary proteins Rsg1 and the Fam92-Chibby-Dzip module
Funded at University of Texas at Austin · NIH-10914661 · Data updated 2026-11-12
This study is looking at how certain proteins might affect the development of facial features, which could help us understand and improve treatments for people with facial differences from birth.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas at Austin NIH-funded |
| Lab location | 1 site (Austin, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $40,494 |
| NIH project number | 5F31DE033290-02 |
| Project ID | NIH-10914661 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with congenital craniofacial disorders or those with a family history of such conditions.
✕Less likely to help
Patients without craniofacial disorders or those unrelated to the genetic factors being studied may not benefit from this research.
What this research studies
This research investigates the role of specific proteins, Rsg1 and the Fam92-Chibby-Dzip module, in the development of craniofacial structures. By using animal models, the study will explore how disruptions in these proteins can lead to congenital facial differences. Researchers will utilize live imaging techniques to observe the cellular functions of these proteins in real-time, as well as biochemical assays to understand their roles in cell membrane structure. The goal is to gain insights into the mechanisms behind craniofacial disorders, potentially leading to better understanding and treatment options.
Why it matters
Potential benefit: If successful, this research could provide critical insights into the causes of congenital craniofacial disorders, leading to improved diagnostic and therapeutic strategies.
How similar studies have gone: Previous research has shown success in understanding the role of ciliary proteins in other developmental disorders, suggesting a promising avenue for this investigation.
Where this research is happening
-
University of Texas at Austin
Austin, United States Active
Researchers
- Principal investigator: Vazquez, Neftali — University of Texas at Austin
- Study coordinator: Vazquez, Neftali
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.