Understanding how certain proteins affect appetite regulation through endocannabinoid signaling
Administrative Supplement to NIH R16 GM145403
This study is looking at how certain proteins in your body help control hunger by working with natural chemicals called cannabinoids, and it aims to find new ways to manage appetite and weight for people dealing with obesity.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | City College of New York NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11035928 on NIH RePORTER |
What this research studies
This research investigates the role of fatty acid-binding proteins (FABPs) in the regulation of appetite through the signaling of endogenous cannabinoids (ECs). By examining how these proteins interact with ECs and their metabolic pathways, the study aims to uncover mechanisms that could influence obesity and appetite control. The research will involve laboratory experiments to analyze the binding and transport of ECs, as well as their effects on cellular signaling. Participants may benefit from insights into how these biological processes can be targeted for better management of appetite and weight-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity or related metabolic disorders.
Not a fit: Patients who do not have issues related to appetite regulation or obesity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing obesity and appetite regulation in patients.
How similar studies have performed: Previous research has shown promising results in understanding the role of endocannabinoids in appetite regulation, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- City College of New York — New York, United States (Active)
Researchers
- Principal investigator: Stark, Ruth E. — City College of New York
- Study coordinator: Stark, Ruth E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.