Understanding how certain proteins affect appetite regulation through endocannabinoid signaling
Molecular Drivers of FABP-mediated Endocannabinoid Signaling for Appetite Regulation
This study is looking at how certain proteins in our body help control our appetite by interacting with natural chemicals, which could help us understand why some people gain weight while others don’t, and it might lead to new ways to help manage weight and eating habits.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | City College of New York NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10889199 on NIH RePORTER |
What this research studies
This research investigates the role of fatty acid-binding proteins (FABPs) in the regulation of appetite through endocannabinoid signaling. By examining how these proteins interact with endogenous cannabinoids (ECs) and their effects on metabolic processes, the study aims to uncover mechanisms that influence whether individuals become obese or maintain a healthy weight. The research will involve laboratory experiments to analyze the binding and transport of ECs, as well as their interactions with specific receptors in the body. Patients may benefit from insights gained that could lead to new treatments for appetite regulation and obesity.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity or those interested in understanding appetite regulation mechanisms.
Not a fit: Patients who are not affected by obesity or appetite regulation issues may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing appetite and obesity, potentially improving weight-related health outcomes.
How similar studies have performed: Previous research has shown promising results in understanding the role of endocannabinoids in appetite regulation, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- City College of New York — New York, United States (Active)
Researchers
- Principal investigator: Stark, Ruth E. — City College of New York
- Study coordinator: Stark, Ruth E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.