Understanding how certain lipoproteins contribute to heart disease
Biogenesis and Catabolism of Atherogenic Lipoproteins
['FUNDING_P01'] · NYU LONG ISLAND SCHOOL OF MEDICINE · NIH-11064044
This study is looking at how certain fats in your blood can lead to heart problems, and it's trying to find new ways to lower those harmful fats to keep your arteries healthy.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NYU LONG ISLAND SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (MINEOLA, UNITED STATES) |
| Trial ID | NIH-11064044 on ClinicalTrials.gov |
What this research studies
This research investigates the production and breakdown of atherogenic lipoproteins, which are linked to cardiovascular disease (CVD). It aims to identify new biological processes and factors that regulate the levels of triglycerides and cholesterol in the body. By studying both human data and new animal models, the research seeks to uncover unique targets that could help reduce harmful lipoproteins and their impact on artery health. The approach combines basic cellular mechanisms with translational insights to improve understanding and treatment of CVD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for cardiovascular disease, particularly those with elevated levels of triglycerides or atherogenic lipoproteins.
Not a fit: Patients who do not have cardiovascular disease risk factors or those with established heart disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for reducing the risk of cardiovascular disease by targeting specific lipoproteins.
How similar studies have performed: Previous research has shown promise in targeting lipoprotein metabolism to reduce cardiovascular risk, indicating that this approach may lead to significant advancements.
Where this research is happening
MINEOLA, UNITED STATES
- NYU LONG ISLAND SCHOOL OF MEDICINE — MINEOLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HUSSAIN, M MAHMOOD — NYU LONG ISLAND SCHOOL OF MEDICINE
- Study coordinator: HUSSAIN, M MAHMOOD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.