Understanding how certain lipids affect nerve cell communication
Regulation of parallel recycling pathways at synaptic sites
This study looks at how certain fats in our bodies help nerve cells work properly and adapt, and it hopes to find out how small changes in these fats can lead to nerve-related issues, which could help improve treatments for people with neurological conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11093343 on NIH RePORTER |
What this research studies
This research investigates the role of specific lipids in the trafficking processes that are essential for the function and adaptability of nerve cells. By examining how minor mutations in these lipid pathways can lead to neurological disorders, the study aims to uncover the mechanisms behind synaptic function and plasticity. Patients may benefit from insights gained about how these pathways can be targeted for therapeutic interventions, potentially improving treatments for various neurological conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation are individuals with genetic mutations affecting synaptic function or those diagnosed with related neurological disorders.
Not a fit: Patients with neurological conditions not associated with lipid signaling pathways may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating neurological disorders linked to lipid signaling pathways.
How similar studies have performed: Previous research has shown promising results in understanding lipid signaling in non-neuronal cells, suggesting potential for success in this area.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Weisman, Lois S — University of Michigan at Ann Arbor
- Study coordinator: Weisman, Lois S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.