Understanding how certain knee features affect the progression of osteoarthritis
Identifying determinants of rapid structural and/or clinical progression in knee osteoarthritis by quantitative assessment of structural features on radiographs
['FUNDING_R01'] · UNIVERSITY OF ARIZONA · NIH-10888249
This study is looking at how certain features in knee images can help doctors figure out which patients with knee osteoarthritis might experience faster worsening of their condition, so they can provide better, personalized treatment.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ARIZONA (nih funded) |
| Locations | 1 site (TUCSON, UNITED STATES) |
| Trial ID | NIH-10888249 on ClinicalTrials.gov |
What this research studies
This research investigates the factors that lead to rapid progression of knee osteoarthritis (KOA) by using advanced software to analyze radiographic images of the knee. The study aims to identify specific structural features that may indicate a higher risk of rapid deterioration in patients with KOA. By employing a quantitative approach, the researchers hope to develop a reliable method for predicting which patients are likely to experience faster progression of their condition. This could ultimately help in tailoring treatment strategies for those at greater risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with knee osteoarthritis who may be experiencing varying rates of disease progression.
Not a fit: Patients with stable knee osteoarthritis who are not at risk for rapid progression may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better identification of patients at risk for rapid knee osteoarthritis progression, allowing for earlier and more targeted interventions.
How similar studies have performed: Previous research has shown promise in using quantitative imaging techniques to assess disease progression in osteoarthritis, indicating that this approach may yield valuable insights.
Where this research is happening
TUCSON, UNITED STATES
- UNIVERSITY OF ARIZONA — TUCSON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KWOH, C KENT — UNIVERSITY OF ARIZONA
- Study coordinator: KWOH, C KENT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.