Understanding how certain immune cells develop and function in infections and cancer
Developmental acquisition of memory-phenotype CD8+ T cell function in infection and cancer
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF CHICAGO · NIH-11071275
This study is looking at a special type of immune cell that helps your body fight infections and cancer, to better understand how these cells work and how they can be used to improve treatments for patients.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CHICAGO (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-11071275 on ClinicalTrials.gov |
What this research studies
This research investigates a specific type of immune cell known as CD8 memory phenotype (CD8-MP) T cells, which play a crucial role in the body's response to infections and cancer. The study aims to uncover how these cells differentiate and function, particularly in the context of recognizing self-antigens and responding to tumors. By analyzing these cells in both infection and cancer settings, the research seeks to provide insights into their potential roles in anti-tumor immunity. This could lead to new strategies for enhancing immune responses in patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with cancer or infections who are interested in understanding their immune response.
Not a fit: Patients with autoimmune diseases or those who do not have a significant immune response may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies that enhance the immune system's ability to fight infections and cancer.
How similar studies have performed: Previous research has shown promising results in understanding immune cell functions, suggesting that this approach could yield valuable insights.
Where this research is happening
CHICAGO, UNITED STATES
- UNIVERSITY OF CHICAGO — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MAHESHWARI, NIKITA — UNIVERSITY OF CHICAGO
- Study coordinator: MAHESHWARI, NIKITA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.