Understanding how certain immune cells develop and function
The role of CD163L1 in CD8+ T cells
['FUNDING_R21'] · CORNELL UNIVERSITY · NIH-10738771
This study is looking at how certain immune cells, called CD8+ T cells, develop into either short-lived fighters or long-lasting memory cells, and it focuses on a special receptor that might help explain these differences, which could lead to better ways to understand and improve our immune responses.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CORNELL UNIVERSITY (nih funded) |
| Locations | 1 site (ITHACA, UNITED STATES) |
| Trial ID | NIH-10738771 on ClinicalTrials.gov |
What this research studies
This research investigates the differentiation of CD8+ T cells, which are crucial for immune responses. It aims to understand why some of these cells become short-lived effectors while others develop into long-lasting memory cells. The study will explore the role of a specific receptor, CD163L1, that is found on fetal-derived CD8+ T cells, potentially revealing new insights into their unique functions. By examining these distinct cell lineages, the research seeks to enhance our understanding of immune responses and memory formation.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are interested in understanding immune cell behavior and its implications for health.
Not a fit: Patients with conditions unrelated to immune function or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for enhancing immune responses in patients, particularly in the context of infections and vaccinations.
How similar studies have performed: Previous research has shown promising results in understanding immune cell differentiation, but the specific role of CD163L1 in this context is relatively novel.
Where this research is happening
ITHACA, UNITED STATES
- CORNELL UNIVERSITY — ITHACA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RUDD, BRIAN DAVID — CORNELL UNIVERSITY
- Study coordinator: RUDD, BRIAN DAVID
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.