Understanding how certain immune cells affect brain function and memory.

Defining the role of meningeal neutrophils in cognition

['FUNDING_OTHER'] · WEST VIRGINIA UNIVERSITY · NIH-10878960

This study is looking at how a type of immune cell called neutrophils helps keep our brains healthy and affects our ability to learn and remember, which could lead to new ways to understand brain health for everyone.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorWEST VIRGINIA UNIVERSITY (nih funded)
Locations1 site (MORGANTOWN, UNITED STATES)
Trial IDNIH-10878960 on ClinicalTrials.gov

What this research studies

This research investigates the role of neutrophils, a type of immune cell, in maintaining brain health and their influence on learning and memory. The study focuses on characterizing the neutrophil population in the protective layers of the brain, known as the meninges, and how their activity may affect neuronal function. By using advanced techniques such as bioinformatics and electrophysiology, the researchers aim to uncover the mechanisms by which these immune cells contribute to cognitive processes. This work could lead to new insights into how immune responses in the brain can impact cognitive health.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with cognitive impairments or neurodegenerative conditions.

Not a fit: Patients with acute infections or those not experiencing cognitive issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for enhancing cognitive function and treating neurodegenerative diseases.

How similar studies have performed: Other research has shown promising results in understanding the immune system's role in brain function, suggesting that this approach could yield valuable insights.

Where this research is happening

MORGANTOWN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.