Understanding how certain genes influence male-specific traits in worms
Official title: The Evolution of Sexually Dimorphic Morphogenesis
Funded at New York University · NIH-11071270 · Data updated 2026-11-12
This study looks at how certain genes help male worms develop their tails, which could teach us more about how male and female traits are shaped in different species.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | January 1, 2025 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $48,974 |
| NIH project number | 1F31GM156032-01A1 |
| Project ID | NIH-11071270 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would be individuals interested in genetic studies related to sexual dimorphism and developmental biology.
✕Less likely to help
Patients with conditions unrelated to genetic factors influencing sexual development may not receive any benefit from this research.
What this research studies
This research investigates the role of specific genes, known as DM domain transcription factors, in the development of male traits using the model organism Caenorhabditis elegans, a type of worm. The study focuses on how these genes control the morphogenesis of tail tip cells during the last larval stage in male worms. By comparing gene activity and regulation, the research aims to uncover the evolutionary constraints and plasticity of these processes. This could provide insights into the genetic mechanisms underlying sexual dimorphism.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of genetic factors influencing sexual development, which may have implications for treating related disorders.
How similar studies have gone: While the specific approach of this research is novel, similar studies have successfully identified genetic factors influencing development in other organisms.
Where this research is happening
-
New York University
New York, United States Active
Researchers
- Principal investigator: Jallad, Raya S — New York University
- Study coordinator: Jallad, Raya S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.