Understanding how certain genes help sensory neurons regenerate and function
Molecular mechanisms underlying sensory neuron regeneration and function
['FUNDING_R01'] · SAN DIEGO STATE UNIVERSITY · NIH-10561598
This study is looking at how certain genes help planarians, a type of flatworm, regrow their sensory nerves, which could lead to new treatments for people with nerve damage or sensory issues.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SAN DIEGO STATE UNIVERSITY (nih funded) |
| Locations | 1 site (SAN DIEGO, UNITED STATES) |
| Trial ID | NIH-10561598 on ClinicalTrials.gov |
What this research studies
This research investigates the role of SoxB1 transcription factors in the regeneration of sensory neurons using the planarian Schmidtea mediterranea as a model organism. By studying how these genes influence stem cell behavior and neuron function, the research aims to uncover the molecular mechanisms that enable tissue regeneration. Patients may benefit from insights gained about sensory neuron regeneration, which could inform future therapies for nerve damage or sensory disorders.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with sensory neuron injuries or disorders affecting nerve regeneration.
Not a fit: Patients with conditions unrelated to sensory neuron function or regeneration may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for conditions involving nerve damage or sensory dysfunction.
How similar studies have performed: Other research has shown promising results in understanding gene functions related to regeneration, but this specific approach using planarians is relatively novel.
Where this research is happening
SAN DIEGO, UNITED STATES
- SAN DIEGO STATE UNIVERSITY — SAN DIEGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZAYAS, RICARDO M. — SAN DIEGO STATE UNIVERSITY
- Study coordinator: ZAYAS, RICARDO M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.