Understanding how certain genes control fat cell development
Non-coding Genomic Determinants of Adipogenesis
['FUNDING_FELLOWSHIP'] · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · NIH-11009928
This study is looking at how our genes help control the growth of fat cells in the body, and it's for anyone interested in understanding the science behind weight gain and fat development.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEW YORK UNIVERSITY SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11009928 on ClinicalTrials.gov |
What this research studies
This research investigates the genetic factors that influence the development of fat cells, known as adipocytes. It focuses on how specific regions of DNA, called enhancers, interact with genes to regulate fat cell formation. By silencing different parts of these enhancers at various stages of fat cell development, researchers aim to uncover the complex signaling pathways involved. This study utilizes advanced techniques to observe and manipulate the interactions between DNA and proteins in individual cells, providing insights into the mechanisms of adipogenesis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in understanding genetic factors related to obesity or metabolic health.
Not a fit: Patients who are not affected by obesity or metabolic disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating obesity and related metabolic disorders by targeting the genetic pathways involved in fat cell development.
How similar studies have performed: Previous research has shown success in understanding gene regulation in other contexts, suggesting that this approach may yield valuable insights into adipogenesis.
Where this research is happening
NEW YORK, UNITED STATES
- NEW YORK UNIVERSITY SCHOOL OF MEDICINE — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WHITNEY, PETER H — NEW YORK UNIVERSITY SCHOOL OF MEDICINE
- Study coordinator: WHITNEY, PETER H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.