Understanding how certain fats influence interactions between humans and gut microbes
Sphingolipid-dependent host-microbe interactions
This study is looking at how certain fats in your body, called sphingolipids, help your gut talk to good bacteria, and it’s for anyone interested in how what we eat can affect our gut health and the tiny microbes living in it.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cornell University NIH-funded |
| Lab location | 1 site (Ithaca, United States) |
| Project ID | NIH-10849659 on NIH RePORTER |
What this research studies
This research investigates the role of sphingolipids, a type of fat, in the communication between the human gut and beneficial microbes. By examining how these molecules are produced and exchanged between hosts and microbes, the study aims to uncover their impact on gut health and microbial communities. Researchers will utilize advanced techniques like mass spectrometry to measure sphingolipids and track their movement between the host and microbes. This could lead to insights on how diet and microbial interactions affect overall health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in gut health, particularly those with conditions related to gut microbiome imbalances.
Not a fit: Patients who do not have any gastrointestinal issues or are not interested in dietary impacts on health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of gut health and lead to new dietary recommendations or therapies that improve microbial balance in the intestines.
How similar studies have performed: Previous research has shown promising results in understanding host-microbe interactions through lipid signaling, indicating that this approach could yield valuable insights.
Where this research is happening
Ithaca, United States
- Cornell University — Ithaca, United States (Active)
Researchers
- Principal investigator: Johnson, Elizabeth L — Cornell University
- Study coordinator: Johnson, Elizabeth L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.