Understanding how certain fat cells develop and function in the body
Transcriptional Control of High-thermogenic Adipocyte Development
['FUNDING_R01'] · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · NIH-11064792
This study is looking at a special type of fat cell that doesn't burn energy as well, to see how it affects obesity and overall health, with the hope of finding new ways to help people manage their weight and improve their metabolism.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR (nih funded) |
| Locations | 1 site (ALBUQUERQUE, UNITED STATES) |
| Trial ID | NIH-11064792 on ClinicalTrials.gov |
What this research studies
This research investigates the different types of fat cells in brown adipose tissue, focusing on a specific group of cells that have lower energy-burning capabilities. The study aims to understand how these cells, known as JunB+ adipocytes, contribute to obesity and metabolic health. By using advanced techniques like single-nucleus RNA sequencing, the researchers will explore how the JunB protein influences the development of these fat cells and their ability to burn energy. The ultimate goal is to uncover new insights that could lead to better treatments for obesity and related metabolic disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 21 and older who are interested in understanding fat cell biology and its implications for obesity.
Not a fit: Patients who are not affected by obesity or metabolic disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating obesity and improving metabolic health.
How similar studies have performed: Other research has shown promising results in understanding fat cell differentiation and its impact on metabolism, suggesting that this approach could yield valuable insights.
Where this research is happening
ALBUQUERQUE, UNITED STATES
- UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR — ALBUQUERQUE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIU, MEILIAN — UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
- Study coordinator: LIU, MEILIAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.