Understanding how certain enzymes interact with lipids in the body
Action of Lipolytic Enzymes
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11003774
This study is looking at how certain enzymes in our bodies interact with fats, which could help us understand how to better treat conditions related to fat metabolism, potentially leading to new therapies for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11003774 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms by which important human enzymes, known as phospholipases, interact with lipid molecules. By studying these interactions at a molecular level, the research aims to uncover how these enzymes are activated and regulated, which could lead to new therapeutic targets. The approach involves examining the structural changes that occur when these enzymes bind to lipid interfaces, potentially revealing new insights into their function. Patients may benefit from findings that could inform the development of treatments for conditions related to lipid metabolism.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with metabolic disorders or conditions related to lipid metabolism.
Not a fit: Patients with conditions unrelated to lipid metabolism or enzyme function may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for diseases linked to lipid metabolism and enzyme regulation.
How similar studies have performed: Previous research has shown promise in understanding enzyme-lipid interactions, suggesting that this approach could yield valuable insights.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DENNIS, EDWARD A — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: DENNIS, EDWARD A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.