Understanding how certain cell structures organize microtubules in animal cells
Mechanisms of non-centrosomal microtubule-organizing center functions
['FUNDING_R01'] · FLORIDA STATE UNIVERSITY · NIH-10782456
This study is looking at special structures in animal cells that help organize tiny tubes called microtubules, which are important for how cells work, especially in fat cells, to better understand how they support different cell functions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | FLORIDA STATE UNIVERSITY (nih funded) |
| Locations | 1 site (TALLAHASSEE, UNITED STATES) |
| Trial ID | NIH-10782456 on ClinicalTrials.gov |
What this research studies
This research investigates the role of non-centrosomal microtubule-organizing centers (ncMTOCs) in animal cells, focusing on their unique structures and functions. By examining how these ncMTOCs assemble microtubules, the study aims to uncover the mechanisms that support various cellular processes, particularly in fat body cells. The research employs advanced biochemical techniques to analyze the molecular architecture and assembly processes of these ncMTOCs, which are crucial for cell function and organization.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that affect cellular function or organization, particularly those related to fat metabolism or cellular trafficking.
Not a fit: Patients with conditions unrelated to cellular organization or those not involving microtubule dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of cellular organization, potentially informing treatments for diseases related to cellular dysfunction.
How similar studies have performed: While the study of ncMTOCs is a relatively novel area, preliminary research has shown promising results in understanding their roles in cellular processes.
Where this research is happening
TALLAHASSEE, UNITED STATES
- FLORIDA STATE UNIVERSITY — TALLAHASSEE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MEGRAW, TIMOTHY L — FLORIDA STATE UNIVERSITY
- Study coordinator: MEGRAW, TIMOTHY L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.