Understanding how certain brain neurons influence eating behavior and responses to food cues

Elucidating the role for MCH neurons in feeding behavior and responses to sensory food cues

['FUNDING_R01'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-10911042

This study looks at how certain brain cells that help control hunger respond to things like food ads and pictures, and it aims to understand why we sometimes crave food even when we're not hungry, which could help find new ways to treat overeating and obesity.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded)
Locations1 site (ANN ARBOR, UNITED STATES)
Trial IDNIH-10911042 on ClinicalTrials.gov

What this research studies

This research investigates the role of melanin-concentrating hormone (MCH) neurons in the brain and how they affect feeding behavior and responses to food-related sensory cues. The study aims to explore how these neurons interact with environmental stimuli, such as advertisements and visual cues, that can trigger cravings for food, even when not hungry. By examining the neural circuits involved, the research seeks to uncover mechanisms that contribute to overeating and obesity. Patients may benefit from insights that could lead to new treatments for eating disorders and obesity.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals struggling with obesity or eating disorders, particularly those influenced by external food cues.

Not a fit: Patients who do not experience issues related to eating behaviors or obesity may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for managing obesity and eating disorders by targeting specific brain pathways.

How similar studies have performed: Previous research has shown promising results in understanding the neural mechanisms of feeding behavior, suggesting that this approach could yield valuable insights.

Where this research is happening

ANN ARBOR, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.