Understanding how certain brain cells regulate learning and memory
Inhibitory regulation of hippocampal CA3 neuron activity, learning, and memory
['FUNDING_R01'] · UNIVERSITY OF UTAH · NIH-11054607
This study is looking at special brain cells that help control learning and memory, and it hopes to find out how they work together to keep our brains balanced, which could help us understand memory-related issues better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF UTAH (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-11054607 on ClinicalTrials.gov |
What this research studies
This research investigates the role of inhibitory neurons in the hippocampus, specifically focusing on how they influence learning and memory processes. By examining a specific group of GABAergic neurons that express a protein called Kirrel3, the study aims to understand how these neurons interact with excitatory neurons to maintain balanced brain activity. The research employs advanced techniques to observe neuron behavior and connectivity, which could lead to insights into neurological disorders. Patients may benefit from findings that enhance our understanding of memory-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with neurological disorders that affect learning and memory, such as autism spectrum disorder or other cognitive impairments.
Not a fit: Patients with purely physical health conditions unrelated to cognitive function may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for memory-related disorders and improve cognitive function in affected patients.
How similar studies have performed: Previous research has shown promising results in understanding the role of GABAergic neurons in brain function, suggesting that this approach could yield valuable insights.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- UNIVERSITY OF UTAH — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WILLIAMS, MEGAN ELISE — UNIVERSITY OF UTAH
- Study coordinator: WILLIAMS, MEGAN ELISE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: autism spectral disorder, autism spectrum disorder, Autistic Disorder, autistic spectrum disorder