Understanding how certain brain cells may contribute to autism.
Developmental Dysfunction of Parvalbumin Interneurons in Autism Spectrum Disorder
This study is looking at how certain brain cells called parvalbumin interneurons might be linked to Autism Spectrum Disorder, with the hope of finding new ways to help improve brain function and support people with ASD.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-10914662 on NIH RePORTER |
What this research studies
This research investigates the role of parvalbumin interneurons, a type of brain cell, in the development of Autism Spectrum Disorder (ASD). It focuses on how disruptions in these cells' functions may affect brain connectivity and cognitive abilities. By examining genetic factors and the specific mechanisms involved, the study aims to uncover how these interneurons contribute to the symptoms of ASD. Patients may benefit from insights that could lead to targeted therapies or interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Autism Spectrum Disorder, particularly those with genetic variations linked to the condition.
Not a fit: Patients without a diagnosis of Autism Spectrum Disorder or those with unrelated neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve cognitive and sensory processing in individuals with autism.
How similar studies have performed: Previous research has shown promising results in understanding the role of GABAergic interneurons in various neurological conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Ward, Claire — Albert Einstein College of Medicine
- Study coordinator: Ward, Claire
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.