Understanding how certain brain cells in the anterior cingulate cortex affect emotions and social behavior
Functional heterogeneity of vasoactive intestinal peptide-expressing interneurons in the anterior cingulate cortex
This study is looking at how certain brain cells in a part of the brain called the anterior cingulate cortex help mice handle feelings and social situations, which could help us understand anxiety and social disorders better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11247440 on NIH RePORTER |
What this research studies
This research investigates the different roles of specific brain cells in the anterior cingulate cortex (ACC) that are involved in emotional processing and social cognition. By using advanced techniques like 3D-printed miniature miniscopes and fluorescent indicators, researchers will monitor the activity of these cells in live mice as they engage in tasks related to anxiety and social interactions. The goal is to uncover how these cells contribute to various behaviors and emotional responses, which could lead to better understanding of conditions like anxiety and social disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing anxiety disorders or social cognitive challenges.
Not a fit: Patients with neurological conditions unrelated to anxiety or social cognition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and treatments for anxiety and social cognitive disorders.
How similar studies have performed: Previous research has shown promising results in understanding brain circuits related to behavior, suggesting that this approach could yield valuable insights.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Cruz-Martin, Alberto — University of Colorado Denver
- Study coordinator: Cruz-Martin, Alberto
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.