Understanding how certain brain cells help control breathing
Identification of chemosensitive cells within the lateral hypothalamus
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF CONNECTICUT STORRS · NIH-10898932
This study is looking at how certain brain cells help control our breathing when carbon dioxide levels change, which is especially important during sleep, and it hopes to find ways to improve understanding of breathing problems that some people might have.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CONNECTICUT STORRS (nih funded) |
| Locations | 1 site (STORRS-MANSFIELD, UNITED STATES) |
| Trial ID | NIH-10898932 on ClinicalTrials.gov |
What this research studies
This research investigates how specific neurons in the lateral hypothalamus of the brain respond to changes in carbon dioxide levels, which is crucial for regulating breathing. By using advanced genetic techniques, the study aims to identify and characterize these neurons, their mechanisms, and their role in maintaining normal breathing patterns, especially during sleep. The research will involve both laboratory experiments and animal models to explore how these neurons contribute to respiratory functions. Patients may benefit from insights gained into breathing disorders linked to hypothalamic function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing breathing difficulties, especially during sleep, which may be linked to brain function.
Not a fit: Patients with breathing issues not related to central nervous system function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for breathing disorders, particularly those that occur during sleep.
How similar studies have performed: While the specific approach of identifying chemosensitive cells in the lateral hypothalamus is novel, similar research has shown promise in understanding brain mechanisms related to respiratory control.
Where this research is happening
STORRS-MANSFIELD, UNITED STATES
- UNIVERSITY OF CONNECTICUT STORRS — STORRS-MANSFIELD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KHUU, MAGGIE ANN — UNIVERSITY OF CONNECTICUT STORRS
- Study coordinator: KHUU, MAGGIE ANN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.