NIH-funded research R15 grant

Understanding how certain bacteria process fatty acids

Official title: Enzymology of Bacteroides short and branched chain fatty acid metabolism

Funded at University of Wisconsin Parkside · NIH-10651505 · Data updated 2026-11-12

This study is looking at how certain bacteria in our gut break down fatty acids and how their genetic differences affect their ability to do this, which could help us understand more about gut health and how these bacteria impact our well-being.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionUniversity of Wisconsin Parkside
NIH-funded
Lab location1 site (Kenosha, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2026
Funding year2023
Award (this year)$372,500
NIH project number1R15GM150186-01
Project IDNIH-10651505 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with gastrointestinal conditions or those interested in the health impacts of gut microbiota.

Less likely to help

Patients who do not have gastrointestinal issues or are not interested in microbiome-related health may not receive direct benefits from this research.

What this research studies

This research investigates the enzymatic processes of specific bacteria, particularly focusing on how they metabolize short and branched chain fatty acids. By examining the genetic variations in these bacteria, the study aims to uncover how these differences affect their enzymatic functions and overall metabolic capabilities. The researchers will employ biochemical and genetic techniques to characterize these enzymes, which could have significant implications for gut health and microbiome function. Patients may benefit from insights gained about how these bacteria influence health through their metabolic activities.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding of gut health and potential therapeutic strategies for conditions related to microbiome imbalances.

How similar studies have gone: Other research has shown promising results in understanding bacterial metabolism and its implications for health, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of Wisconsin Parkside
    Kenosha, United States
    Active

Researchers

  • Principal investigator: Barber, Robert — University of Wisconsin Parkside
  • Study coordinator: Barber, Robert

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.