Understanding how certain bacteria manage their genetic material during reproduction
Official title: Development-Associated Linear Chromosome Segregation in Streptomyces
Funded at Duquesne University · NIH-10579038 · Data updated 2026-11-12
This study is looking at a type of bacteria called Streptomyces, which helps make important medicines like antibiotics, to learn how they manage their genetic material when they create spores, and this could help us find better ways to use these bacteria in medicine.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duquesne University NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | September 20, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $401,069 |
| NIH project number | 1R15GM148966-01 |
| Project ID | NIH-10579038 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients who may benefit from this research include those with bacterial infections that are resistant to current treatments.
✕Less likely to help
Patients with non-bacterial infections or those not affected by antibiotic-resistant bacteria may not receive benefits from this research.
What this research studies
This research focuses on Streptomyces, a type of bacteria known for producing important medicines like antibiotics. The study aims to explore how these bacteria organize and segregate their genetic material during their unique life cycle, particularly during spore formation. By using genetic techniques, researchers will investigate a specific protein that may play a crucial role in this process. This understanding could lead to advancements in how we utilize these bacteria for medical purposes.
Why it matters
Potential benefit: If successful, this research could enhance the development of new antibiotics and other therapeutic agents derived from Streptomyces.
How similar studies have gone: Other research has shown success in understanding bacterial genetics and its implications for antibiotic production, making this approach promising.
Where this research is happening
-
Duquesne University
Pittsburgh, United States Active
Researchers
- Principal investigator: Mc Cormick, Joseph R — Duquesne University
- Study coordinator: Mc Cormick, Joseph R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.