Understanding how certain bacteria in the nose interact to promote health.

Mechanisms of Corynebacterium-Dolosigranulum Interactions that Shape Human Nasal Microbiota

NIH-funded research Baylor College of Medicine · NIH-11052624

This study is looking at how two types of bacteria in your nose work together to keep it healthy, which could help prevent infections, and the findings might lead to new ways to protect your respiratory health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBaylor College of Medicine NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-11052624 on NIH RePORTER

What this research studies

This research investigates the interactions between two types of bacteria, Corynebacterium species and Dolosigranulum pigrum, that are found in the human nasal microbiota. The goal is to uncover the molecular mechanisms that allow these bacteria to work together to create a healthy nasal environment, which may help prevent infections. By studying these interactions both in laboratory settings and in real-life scenarios, the research aims to establish a causal relationship between these bacteria and overall nasal health. Patients may benefit from insights that could lead to new strategies for preventing respiratory infections.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with a diverse nasal microbiota, particularly those with high levels of Corynebacterium and D. pigrum.

Not a fit: Patients who do not have a significant presence of Corynebacterium or D. pigrum in their nasal microbiota may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new ways to enhance nasal health and reduce the risk of respiratory infections.

How similar studies have performed: Previous research has shown promising results in understanding the role of nasal microbiota in health, suggesting that this approach could yield valuable insights.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.