Understanding how certain bacteria communicate in the human microbiome
Talking with Small Molecules: Corynebacteria in the Human Microbiome
This study is looking at how certain bacteria on our skin and in our noses talk to each other using tiny chemical signals, which could help us understand how they affect our health and how we can better manage infections caused by them.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Princeton University NIH-funded |
| Lab location | 1 site (Princeton, UNITED STATES) |
| Project ID | NIH-11038877 on NIH RePORTER |
What this research studies
This research investigates how corynebacteria, which are common residents of the skin and upper respiratory tract, communicate using small molecules. By analyzing the chemical signals they produce, the study aims to uncover how these bacteria compete with each other and interact with other microbes and human cells. The researchers will use advanced techniques to identify these chemical signals and understand their roles in health and disease. This could provide insights into how to manage infections caused by these bacteria.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with skin or respiratory conditions related to corynebacterial infections.
Not a fit: Patients who do not have any bacterial infections or related health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating infections caused by multidrug-resistant bacteria.
How similar studies have performed: Other research has shown promise in understanding bacterial communication and its implications for health, making this approach both relevant and potentially impactful.
Where this research is happening
Princeton, UNITED STATES
- Princeton University — Princeton, United States (Active)
Researchers
- Principal investigator: Seyedsayamdost, Mohammad R — Princeton University
- Study coordinator: Seyedsayamdost, Mohammad R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.