Understanding how certain bacteria can live in the body without causing symptoms
Official title: Characterization of Neisseria factors required for asymptomatic carriage
Funded at University of Arizona · NIH-11051167 · Data updated 2026-11-12
This study is looking at how certain Neisseria bacteria can live in the body without making people sick, using mice to learn more about how these bacteria work and interact with their host, which could help us find better ways to handle infections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | March 6, 2024 |
| Project end | February 28, 2026 |
| Funding year | 2025 |
| Award (this year) | $108,000 |
| NIH project number | 5K22AI174066-02 |
| Project ID | NIH-11051167 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would include individuals who are carriers of Neisseria bacteria or those at risk of infection.
✕Less likely to help
Patients who have already developed symptomatic Neisseria infections may not benefit directly from this research.
What this research studies
This research investigates the factors that allow Neisseria bacteria, which can cause infections, to exist in the body without causing symptoms. By studying both pathogenic and commensal Neisseria in a mouse model, the researchers aim to uncover the biological mechanisms behind asymptomatic infections. The approach involves examining specific bacterial features and their interactions with the host, which could lead to new insights into how these bacteria behave and how we can better manage infections. The study will utilize advanced techniques to analyze bacterial behavior and genetic factors involved in this process.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating Neisseria infections, particularly in asymptomatic carriers.
How similar studies have gone: Previous research has shown promise in understanding bacterial behavior through similar approaches, indicating potential for success in this area.
Where this research is happening
-
University of Arizona
Tucson, United States Active
Researchers
- Principal investigator: Rhodes, Katherine — University of Arizona
- Study coordinator: Rhodes, Katherine
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.