Understanding how cerebellar neurotransmission affects brain development.
Unraveling the Dynamic Role of Purkinje Cell Neurotransmission in Neurodevelopment.
This study is looking at how certain brain cells in the cerebellum work during important stages of brain development and how problems with these cells might lead to developmental disabilities, especially in kids born prematurely or with brain injuries, to help find better ways to support them.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11098550 on NIH RePORTER |
What this research studies
This research investigates the role of Purkinje cell neurotransmission in the cerebellum during critical periods of brain development, particularly focusing on how disruptions can lead to neurodevelopmental disabilities. By using advanced genetic techniques in mice, the study aims to manipulate cerebellar function and observe the resulting changes in brain structure, physiology, and behavior. The goal is to gain insights that could inform future interventions for conditions arising from premature birth and related brain injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants and children who have experienced prematurity or related neurodevelopmental challenges.
Not a fit: Patients who are not affected by prematurity or do not have neurodevelopmental disabilities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating neurodevelopmental disabilities associated with prematurity.
How similar studies have performed: Previous research has shown promising results in understanding cerebellar function and its impact on neurodevelopment, suggesting that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Gill, Jason Singh — Baylor College of Medicine
- Study coordinator: Gill, Jason Singh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.