Understanding how cellular aging affects health and disease
Elucidating Cellular Aging and Quality Control Pathways through Meiotic Differentiation
This study is looking at how our cells age and how that affects diseases like cancer and brain disorders, with the hope of finding ways to help our cells stay healthy longer, which could benefit patients dealing with age-related issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project ID | NIH-11083666 on NIH RePORTER |
What this research studies
This research investigates the mechanisms of cellular aging and how they contribute to diseases like cancer and neurodegeneration. By focusing on the differentiation of reproductive cells, the study aims to uncover rejuvenation pathways that can eliminate age-related cellular damage. The approach involves manipulating these pathways to better understand their role in aging and disease prevention. Patients may benefit from insights gained about how to counteract age-related dysfunctions and improve healthspan.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing age-related health issues or those interested in understanding the biological mechanisms of aging.
Not a fit: Patients who are not experiencing age-related conditions or who are significantly younger may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing age-related diseases and improving overall health in older adults.
How similar studies have performed: Other research has shown promise in understanding aging mechanisms, but this approach focusing on gametogenesis and rejuvenation pathways is relatively novel.
Where this research is happening
Berkeley, United States
- University of California Berkeley — Berkeley, United States (Active)
Researchers
- Principal investigator: Unal, Elcin — University of California Berkeley
- Study coordinator: Unal, Elcin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.