Understanding how cells transport potassium and zinc ions
Molecular Mechanisms of Ion Transport
This study looks at how cells keep the right levels of potassium and zinc, which are important for their health, using special tools to see how the proteins that help with this work.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11055309 on NIH RePORTER |
What this research studies
This research investigates the molecular mechanisms that cells use to maintain the balance of potassium and zinc ions, which are crucial for various cellular functions. The team employs advanced techniques such as cryo-electron microscopy and single-molecule fluorescence resonance energy transfer to visualize and analyze the structures and dynamics of the transport proteins involved. By exploring the energy landscapes and regulatory mechanisms of these transport systems, the research aims to provide insights into how these proteins function at a molecular level.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions linked to potassium or zinc ion imbalances, such as certain metabolic disorders.
Not a fit: Patients with conditions unrelated to ion transport or those who do not have any metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for conditions related to ion transport dysregulation.
How similar studies have performed: Other research has shown success in understanding ion transport mechanisms, indicating that this approach is built on established scientific foundations.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Stokes, David L. — New York University School of Medicine
- Study coordinator: Stokes, David L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.