Understanding how cells stick together and communicate
Molecular Mechanisms of Cell Adhesion
This study looks at how cells stick together and to their surroundings, which is important for keeping our tissues healthy, and it could help us understand how problems with these connections might lead to diseases like cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-11123114 on NIH RePORTER |
What this research studies
This research investigates the mechanisms that allow cells to adhere to each other and to their surrounding environment. By focusing on structures known as adherens junctions and focal adhesions, the study aims to uncover how these connections regulate important processes like tissue integrity, cell migration, and proliferation. The research employs biochemical techniques and live-cell imaging to explore the dynamic nature of these cell junctions and their role in maintaining healthy tissue function. Patients may benefit from insights gained into how disruptions in these processes can lead to diseases such as cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to cell adhesion dysfunction, including certain types of cancer.
Not a fit: Patients with conditions unrelated to cell adhesion mechanisms may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating diseases related to cell adhesion, such as cancer.
How similar studies have performed: Previous research has shown promising results in understanding cell adhesion mechanisms, indicating that this approach has the potential for significant advancements.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Izard, Tina — University of Florida
- Study coordinator: Izard, Tina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.