Understanding how cells shape themselves
Origins of Cell Geometry
This study looks at how the shape and size of cells can impact their functions and how they might relate to diseases, using different models and advanced tools to learn more about how cells change their geometry.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11013421 on NIH RePORTER |
What this research studies
This research investigates the complex structures of cells and how their geometry affects their functions, particularly in relation to diseases. By using various model organisms and advanced techniques from physics and engineering, the study aims to uncover the mechanisms behind cell shape and size regulation. The research focuses on both individual organelles and the overall morphology of cells, providing insights into how cells sense and adapt their geometry. This knowledge could lead to a better understanding of cellular processes and disease mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions linked to abnormal cell geometry, such as certain types of cancer.
Not a fit: Patients with stable, normal cell geometry or those without cellular abnormalities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating diseases associated with abnormal cell shapes.
How similar studies have performed: Other research has shown promise in understanding cellular structures and their implications in disease, suggesting that this approach could yield valuable insights.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Marshall, Wallace — University of California, San Francisco
- Study coordinator: Marshall, Wallace
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.