Understanding how cells shape the face during development and congenital conditions
Signaling control and cellular basis of craniofacial morphogenesis and congenital disease
This study is looking at how certain cells in the body can cause facial birth defects, and it's using advanced technology to better understand these processes, which could help improve treatments for those affected.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11086726 on NIH RePORTER |
What this research studies
This research investigates the cellular processes that lead to craniofacial anomalies, which are common birth defects affecting the structure of the face. By utilizing advanced imaging techniques and human stem cell models, the team aims to uncover the cellular behaviors that contribute to these conditions. The study focuses on understanding how specific cellular movements and interactions can lead to abnormal facial development. Patients may benefit from insights gained into the mechanisms behind these congenital conditions, potentially leading to improved treatments and interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with congenital craniofacial anomalies or those at risk of developing such conditions.
Not a fit: Patients without craniofacial anomalies or those not at risk for these conditions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for individuals with craniofacial anomalies.
How similar studies have performed: Previous research has shown promise in understanding craniofacial development, but this approach utilizing human stem cell models is relatively novel.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Bush, Jeffrey Ohmann — University of California, San Francisco
- Study coordinator: Bush, Jeffrey Ohmann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.