Understanding how cells shape and develop into tissues and organs
Synthetic development: dissection of morphogenetic programs via reconstructive and perturbative approaches
['FUNDING_OTHER'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-10891581
This study is looking at how embryos grow and take shape, focusing on the signals between cells and their surroundings, to better understand what goes wrong in conditions that affect development, with the hope of finding new ways to treat these issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTHERN CALIFORNIA (nih funded) |
| Locations | 1 site (Los Angeles, UNITED STATES) |
| Trial ID | NIH-10891581 on ClinicalTrials.gov |
What this research studies
This research investigates the fundamental processes of morphogenesis, which is how embryos develop their shapes and structures. By examining the complex signaling networks among cells and how they interact with their environment, the project aims to uncover the genetic and cellular mechanisms that guide normal development. Utilizing advanced techniques like single-cell sequencing and computational modeling, the researchers will analyze how changes in genes and cellular conditions can lead to congenital disorders. This work seeks to provide insights that could inform future treatments for developmental diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with congenital disorders or those interested in the genetic and developmental aspects of such conditions.
Not a fit: Patients with fully developed and non-congenital conditions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating congenital disorders by enhancing our understanding of embryonic development.
How similar studies have performed: Other research in developmental biology has shown promising results using similar approaches, indicating a strong potential for success in this area.
Where this research is happening
Los Angeles, UNITED STATES
- UNIVERSITY OF SOUTHERN CALIFORNIA — Los Angeles, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MORSUT, LEONARDO — UNIVERSITY OF SOUTHERN CALIFORNIA
- Study coordinator: MORSUT, LEONARDO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Congenital Disorders