Understanding how cells respond to their environment

Regulation of Intracellular Signaling

NIH-funded research Johns Hopkins University · NIH-11055998

This study is looking at how cells respond to different challenges in their environment, like how they move, fix damaged DNA, and grow when certain signals are blocked, which could help us understand important processes for healing and immune health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11055998 on NIH RePORTER

What this research studies

This research investigates how cells control their internal signaling mechanisms to adapt to various environmental challenges. It focuses on three main areas: the movement of cells in response to chemical signals, the repair of DNA after damage from stress, and how cell growth signaling is altered when certain receptors are inhibited. By utilizing advanced technologies and models, the research aims to uncover fundamental processes that are crucial for tissue development, healing, and immune responses.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with conditions that involve impaired cell signaling, such as cancer or chronic wounds.

Not a fit: Patients with stable conditions that do not involve cellular signaling issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for enhancing tissue repair and improving immune responses in patients.

How similar studies have performed: Other research has shown promising results in understanding cellular signaling pathways, indicating that this approach has potential for significant advancements.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.