Understanding how cells respond to a specific type of inflammatory cell death.
Pyroptosis is a Trial-by-Fire Program
['FUNDING_OTHER'] · UNIVERSITY OF ILLINOIS AT CHICAGO · NIH-10894242
This study is looking at a special way that cells can die and how some cells manage to survive this process, which could help us find new treatments for inflammation and healing in patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ILLINOIS AT CHICAGO (nih funded) |
| Locations | 1 site (Chicago, UNITED STATES) |
| Trial ID | NIH-10894242 on ClinicalTrials.gov |
What this research studies
This research investigates pyroptosis, a unique form of inflammatory cell death that occurs in various cell types and is crucial for processes like development and tissue repair. The study aims to understand how some cells can survive this process and what roles the genes involved in pyroptosis play beyond causing cell death. By exploring the mechanisms that control pyroptosis and the effects on individual cells, the research seeks to uncover new insights into cell signaling and potential therapeutic targets. Patients may benefit from advancements in treatments related to inflammation and tissue regeneration.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions involving inflammation or tissue injury.
Not a fit: Patients with stable, non-inflammatory conditions may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance tissue repair and regeneration following injury or inflammation.
How similar studies have performed: Other research has shown promising results in understanding cell death mechanisms, but this specific approach to pyroptosis is relatively novel.
Where this research is happening
Chicago, UNITED STATES
- UNIVERSITY OF ILLINOIS AT CHICAGO — Chicago, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MO, GARY CH — UNIVERSITY OF ILLINOIS AT CHICAGO
- Study coordinator: MO, GARY CH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.