Understanding how cells protect themselves from age-related amino acid toxicity
Investigating the Lysosome and Plasma Membrane Systems in Protecting Cells Against Age-induced Amino Acid Toxicity
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF UTAH · NIH-11041042
This study is looking at how our cells protect themselves from harmful effects of amino acids as we get older, especially in relation to diseases like Alzheimer's and Parkinson's, to find ways to keep our cells healthy and strong as we age.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF UTAH (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-11041042 on ClinicalTrials.gov |
What this research studies
This research investigates the cellular mechanisms that help protect against the toxic effects of amino acids as we age, particularly focusing on the lysosome and plasma membrane systems. The study aims to identify key genes that play a role in maintaining cellular health during aging, especially in the context of diseases like Alzheimer's and Parkinson's. By examining how these cellular processes change with age, the research seeks to uncover potential therapeutic targets that could improve cellular function and resilience. Patients may benefit from insights gained about how to mitigate age-related cellular dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who are at risk for or experiencing symptoms of age-related diseases.
Not a fit: Patients who are younger and do not have any age-related conditions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating age-related diseases such as Alzheimer's and Parkinson's.
How similar studies have performed: Previous research has shown promising results in understanding cellular aging processes, but this specific approach focusing on lysosomal function in relation to amino acid toxicity is relatively novel.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- UNIVERSITY OF UTAH — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHUI, KEVIN — UNIVERSITY OF UTAH
- Study coordinator: CHUI, KEVIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: age associated disease, age associated disorder