Understanding how cells process signals to respond to their environment
Elucidating the network design principles of biological signal processing
This study looks at how cells, from tiny single-celled organisms to the ones in our bodies, detect and react to different signals around them, helping us understand how they make decisions and work together, especially when facing stress.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10909806 on NIH RePORTER |
What this research studies
This research investigates how cells, from single-celled organisms to those in our bodies, sense and respond to various signals in their environment. It focuses on biological signaling pathways that consist of sensors and proteins, which help cells process external signals and communicate internally. By studying how these pathways work, the research aims to uncover how cells make decisions and how these decisions impact the behavior of cellular communities. The project specifically examines the dynamics of signaling networks and transcription factors in response to environmental stress.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that involve cellular signaling abnormalities, such as certain cancers or metabolic disorders.
Not a fit: Patients with conditions unrelated to cellular signaling or those who do not have any cellular dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of cellular decision-making processes, potentially informing treatments for diseases related to cell signaling dysfunction.
How similar studies have performed: Other research has shown success in understanding cellular signaling pathways, indicating that this approach has a solid foundation in existing scientific knowledge.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Mcclean, Megan N — University of Wisconsin-Madison
- Study coordinator: Mcclean, Megan N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.