Understanding how cells organize biomolecules into functional clusters
Official title: Physical laws to control and regulate composition of multi-component biomolecular condensates
Funded at Rutgers, the State Univ of N.j. · NIH-10911328 · Data updated 2026-11-12
This study is looking at how cells form special groups of molecules that help them work properly, and it aims to find new ways to create medicines that could improve treatments for different health issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers, the State Univ of N.j. NIH-funded |
| Lab location | 1 site (Piscataway, United States) |
| Project start | August 22, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $358,364 |
| NIH project number | 5R35GM150589-02 |
| Project ID | NIH-10911328 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions related to cellular dysfunction or diseases influenced by biomolecular condensates.
✕Less likely to help
Patients with conditions unrelated to biomolecular interactions or those not affected by cellular compartmentalization may not benefit from this research.
What this research studies
This research investigates how cells create and regulate clusters of biomolecules, known as membraneless organelles, which play crucial roles in various biological functions. By studying the physical laws and molecular interactions that govern these clusters, the research aims to develop theoretical models that can predict how different biomolecules interact and contribute to cellular processes. This understanding could lead to the development of new drugs targeting disease-related biomolecular condensates, potentially improving treatment options for various conditions.
Why it matters
Potential benefit: If successful, this research could lead to innovative drug therapies that target specific biomolecular clusters involved in diseases.
How similar studies have gone: Other research has shown promise in understanding biomolecular phase separation, indicating that this approach could yield significant insights and advancements.
Where this research is happening
-
Rutgers, the State Univ of N.j.
Piscataway, United States Active
Researchers
- Principal investigator: Dignon, Gregory — Rutgers, the State Univ of N.j.
- Study coordinator: Dignon, Gregory
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.