Understanding how cells move towards chemical signals
Multi-cue Guidance of Mesenchymal Cell Migration
['FUNDING_R01'] · NORTH CAROLINA STATE UNIVERSITY RALEIGH · NIH-10775691
This study is looking at how special healing cells move in response to signals in their surroundings, which could help us find better ways to speed up wound healing and tackle heart-related issues.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTH CAROLINA STATE UNIVERSITY RALEIGH (nih funded) |
| Locations | 1 site (RALEIGH, UNITED STATES) |
| Trial ID | NIH-10775691 on ClinicalTrials.gov |
What this research studies
This research investigates how mesenchymal cells, which play a crucial role in healing and various diseases, migrate in response to chemical signals in their environment. By studying the mechanisms of chemotaxis, particularly how cells respond to gradients of growth factors like PDGF, the research aims to uncover the complex interactions that guide cell movement. The approach combines advanced engineering techniques with biological assays to analyze how different conditions affect cell behavior over time. This knowledge could lead to improved strategies for enhancing wound healing and addressing cardiovascular diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cardiovascular disorders or those requiring enhanced wound healing.
Not a fit: Patients with conditions unrelated to cell migration or those not experiencing cardiovascular issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance healing processes and improve outcomes for patients with cardiovascular diseases.
How similar studies have performed: Previous research has shown promising results in understanding cell migration, but this specific approach to multi-cue guidance is relatively novel.
Where this research is happening
RALEIGH, UNITED STATES
- NORTH CAROLINA STATE UNIVERSITY RALEIGH — RALEIGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HAUGH, JASON M. — NORTH CAROLINA STATE UNIVERSITY RALEIGH
- Study coordinator: HAUGH, JASON M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: cardiovascular disorder, Cardiovascular Diseases