Understanding how cells move together in the body
Deciphering mechanisms that drive collective cell migration
This study is looking at how a special signal in our cells helps them move together, which is important for healing and repairing tissues, and it could lead to better ways to manage healing and treat cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10928248 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind collective cell migration, which is essential for tissue construction and repair. The team will explore how a specific intracellular signal, PLCg1, influences cell movement and behavior. By developing advanced tools and cellular models, they aim to uncover how PLCg1 activation leads to changes in the cell's structure and movement. This knowledge could help in controlling cell migration, which is crucial for healing and cancer treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that involve tissue repair or cancer, particularly those affected by breast cancer.
Not a fit: Patients with non-cancerous conditions unrelated to cell migration or tissue repair may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing tissue repair and developing cancer therapies.
How similar studies have performed: Previous research has shown promising results in understanding cell migration mechanisms, indicating that this approach has potential for success.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Kreeger, Pamela K — University of Wisconsin-Madison
- Study coordinator: Kreeger, Pamela K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.