Understanding how cells move together during healing and development
Models of collective migration that integrate single-cell polarity and mechanics
['FUNDING_OTHER'] · JOHNS HOPKINS UNIVERSITY · NIH-10885977
This study looks at how groups of cells move together, which is important for healing wounds and developing tissues, and by understanding how these cells talk to each other, researchers hope to create computer models that can help us learn more about healing and find better treatments for conditions related to cell movement.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10885977 on ClinicalTrials.gov |
What this research studies
This research investigates how groups of cells migrate collectively, which is essential for processes like wound healing and development. By studying the interactions between individual cells and how they communicate through specific proteins, the researchers aim to create computer models that simulate these movements. This approach will help bridge the gap between molecular interactions and the overall behavior of cell groups, providing insights into how changes in these interactions can affect migration patterns. Patients may benefit from improved understanding of healing processes and potential therapies for conditions involving cell migration.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that involve impaired wound healing or abnormal cell migration.
Not a fit: Patients with conditions unrelated to cell migration or those not experiencing issues with healing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance wound healing and address diseases related to cell migration.
How similar studies have performed: Other research has shown success in using computational models to understand cell behavior, indicating that this approach has potential for meaningful insights.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CAMLEY, BRIAN A — JOHNS HOPKINS UNIVERSITY
- Study coordinator: CAMLEY, BRIAN A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.