Understanding how cells move in tight spaces
Molecular Mechanisms of Confined Cell Migration
This study is looking at how certain cells, like cancer and immune cells, move quickly in tight spaces, which is important for things like healing and how cancer spreads, and it aims to find out what helps them move this way so we can better understand their behavior in different situations.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albany Medical College NIH-funded |
| Lab location | 1 site (Albany, United States) |
| Project ID | NIH-10872139 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind how cells migrate, particularly in confined environments, which is crucial for processes like embryonic development, immune responses, and cancer spread. The study focuses on a specific type of cell movement called fast amoeboid migration, which occurs when cells are under mechanical confinement. By using both laboratory and live animal models, the researchers aim to uncover the molecular factors that enable both cancer and immune cells to switch to this migration mode. This knowledge could lead to better understanding of how these cells behave in various physiological and pathological contexts.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals with cancer or those with conditions affecting immune cell function.
Not a fit: Patients with non-cancerous conditions unrelated to cell migration or immune function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating cancer and improving immune responses.
How similar studies have performed: Previous research has shown success in understanding cell migration mechanisms, but this specific focus on confined environments is relatively novel.
Where this research is happening
Albany, United States
- Albany Medical College — Albany, United States (Active)
Researchers
- Principal investigator: Logue, Jeremy S — Albany Medical College
- Study coordinator: Logue, Jeremy S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.