Understanding how cells move in response to different signals in their environment
Official title: Directed Cell Motility Along Gradients in Extracellular Matrix Fiber Alignment
Funded at Rochester Institute of Technology · NIH-11037032 · Data updated 2026-11-12
This study is looking at how different types of cells, like those involved in cancer and the immune system, move and respond to their surroundings, which could help improve treatments for cancer and tissue repair.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rochester Institute of Technology NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | August 10, 2022 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $99,307 |
| NIH project number | 3R16GM146687-03S1 |
| Project ID | NIH-11037032 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve abnormal cell migration, such as cancer or inflammatory diseases.
✕Less likely to help
Patients with stable conditions that do not involve cell migration issues may not benefit from this research.
What this research studies
This research investigates how cells migrate in response to various signals in their surroundings, particularly focusing on the alignment of fibers and biochemical cues in a 3D environment. By creating a specialized platform that mimics these conditions, researchers aim to uncover how cells prioritize different guidance cues during their movement. The study will involve endothelial, immune, and cancer cells to explore their migratory behavior in a controlled setting. The findings could lead to advancements in therapies that either promote or inhibit cell migration, which is crucial in cancer treatment and tissue engineering.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for controlling cell movement in diseases like cancer.
How similar studies have gone: Previous research has shown promising results in understanding cell migration through similar experimental approaches, indicating potential for success in this study.
Where this research is happening
-
Rochester Institute of Technology
Rochester, United States Active
Researchers
- Principal investigator: Abhyankar, Vinay V — Rochester Institute of Technology
- Study coordinator: Abhyankar, Vinay V
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.