Understanding how cells move in response to different signals in their environment
Directed Cell Motility Along Gradients in Extracellular Matrix Fiber Alignment
['FUNDING_OTHER'] · ROCHESTER INSTITUTE OF TECHNOLOGY · NIH-10872243
This study is looking at how different signals in their environment help cells, like those involved in blood vessels and cancer, move around, which could lead to better treatments for diseases where cell movement is important.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ROCHESTER INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (ROCHESTER, UNITED STATES) |
| Trial ID | NIH-10872243 on ClinicalTrials.gov |
What this research studies
This research investigates how cells migrate in response to various signals in their surroundings, particularly focusing on the alignment of fibers and biochemical cues in a 3D environment. By creating a controlled experimental setup, researchers will expose different types of cells, including endothelial and cancer cells, to these signals to see how they influence cell movement. The goal is to uncover the relationships between different guidance cues that affect cell migration, which could lead to advancements in therapies for diseases where cell movement plays a critical role.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to abnormal cell migration, such as cancer or inflammatory diseases.
Not a fit: Patients with stable conditions that do not involve cell migration or those who are not undergoing treatment for related diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for controlling cell migration in diseases such as cancer.
How similar studies have performed: Previous research has shown promise in understanding cell migration through similar experimental approaches, indicating potential for success in this area.
Where this research is happening
ROCHESTER, UNITED STATES
- ROCHESTER INSTITUTE OF TECHNOLOGY — ROCHESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ABHYANKAR, VINAY V — ROCHESTER INSTITUTE OF TECHNOLOGY
- Study coordinator: ABHYANKAR, VINAY V
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers